BME 5050-0

Brief

This course aims to introduce the cutting-edge technologies and major challenges of cell-ba<x>sed regenerative therapies. In addition to lecture, we will have a paper discussion session each week. Furthermore, students are expected to report their experimental results in the field of cell therapy every week.

Description

Course keywords: 再生醫學, 細胞治療, 幹細胞, 細胞遞送, 胞外囊泡, regenerative medicine, cell therapy, stem cell, cell delivery, extracellular vesicle References 1. Dwaine F. Emerich and Gorka Orive, Cell Therapy: Current status and future directions, Humana Press, New York, 2018 (ISBN 978-3-319-57153-9) 2. Journal papers Teaching Method Lectures, discussion, students’ oral presentation Syllabus 1. Course introduction 2. Current status and challenges of cell-based regenerative therapies 3. Molecular mechanisms of cell therapy-induced regeneration 4. Strategies for tracing the transplanted cells 5. Animal models for evaluating the efficacy of cell therapies 6. Biomaterials for cell therapy (I): Cell encapsulation 7. Biomaterials for cell therapy (II): Scalable cell production 8. Midterm exam 9. Cell-derived products as therapeutics (I): Extracellular vesicles 10. Cell-derived products as therapeutics (II): Mitochondria 11. Regulations for cell therapy 12. GTP/GMP Cell Manufacturing Facilities 13. Cell-based therapies for cardiovascular diseases 14. Cell-based therapies for neurodegenerative diseases 15. Cell-based therapies for musculoskeletal disorders 16. Cell-based therapies for diabetes mellitus 17. Term project presentation 18. Final exam Evaluation Midterm exam: 25% Final exam: 25% Term project: 20% Class discussion: 20% Attendance: 10%

Timetable

Scores

Average GPA 4.3

Std. Deviation 0

Remarks

1.需與授課教師討論後加簽選課 2.本課程為16週課程

Restrictions

Compulsory

Elective

Cross Discipline

First Specialization

Second Specialization